Alienation

Alienation is the first of the Nine Plagues. It is a phenomenon of alienation from your fellow Sapients.

Its vaccine is The Pride.

Many things can cause and exacerbate Alienation including the master slave dialectic, bigotry, prejudice, individualism, and victim blaming, and the just world hypothesis

Betrayal is considered a sin against sapience because it can induce alienation. Rape is one that specifically damages Eusexuality.