Alienation

Alienation is one of the Nine Plagues. It is a phenomenon of alienation from your fellow Sapients. It is the worst plague because it keeps you from finding a community to implement the ninefold vaccine with, and thus gives you the Plato's Lion problem.

Its vaccine is The Pride.

Many things can cause and exacerbate Alienation including the master slave dialectic, bigotry, prejudice, individualism, and victim blaming, and the just world hypothesis

Betrayal is considered a sin against sapience because it can induce alienation. Rape is one that specifically damages Eusexuality.